In magic mushrooms, menopause, microdosing, psilocybin, psychedelics

Microdosing has gained considerable attention in recent years, particularly in the realm of mental health and personal development. As a physician and integrative medicine expert, I’ve seen firsthand the impact that this innovative approach can have on individuals seeking to improve their well-being, including for women dealing with menstrual pain, PMS, PMDD and menopausal symptoms.

In this blog post, I will explore the concept of sub-hallucinogenic doses and the appropriate frequency of administration in the context of microdosing psychedelics.

Understanding Sub-Hallucinogenic Doses:

Microdosing involves the administration of very small doses of psychedelic substances, such as psilocybin (found in “magic mushrooms”) or LSD. These doses are intentionally kept low to avoid the intense, often overwhelming experiences associated with a full psychedelic “trip.” Instead, microdosing aims to provide subtle benefits in mood, cognition, and creativity, without impairing day-to-day functioning.

The key to microdosing lies in finding the right balance. A sub-hallucinogenic dose typically falls in the range of 1/10th to 1/20th of a recreational dose. For example, a microdose of psilocybin may be around 0.1 to 0.3 grams of dried mushrooms, while a microdose of LSD may be approximately 10 to 20 micrograms. It’s important to note that individual sensitivities and tolerances may vary, so some experimentation may be necessary to determine the most suitable dose for each person.

Frequency of Administration:

When it comes to microdosing, finding the right frequency of administration is crucial to optimize the benefits and minimize potential risks. Most microdosing protocols recommend following a schedule that allows for sufficient rest and integration between doses. A common approach is the “Fadiman protocol,” named after Dr. James Fadiman, a leading researcher in the field of psychedelics.

The Fadiman protocol suggests taking a microdose once every three days. This consists of one day on (dosing), followed by two days off (no dosing). This pattern allows individuals to observe and assess the effects of the microdose, integrate the experience, and prevent the development of tolerance to the psychedelic substance.

Insights on Microdosing for Women

Dr. James Fadiman, author of “The Psychedelic Explorer’s Guide” and a pioneer in psychedelic research, has observed the potential benefits of microdosing for women’s health.

We’ve had a number of reports, unsolicited, from women saying, ‘I had the easiest period of my life. I don’t know what’s going on.’

~ Dr. James Fadiman

Exploring the Stamets Protocol

Another prominent microdosing protocol is the “Stamets protocol,” developed by renowned mycologist and psychedelic advocate Paul Stamets. The Stamets protocol is slightly different from the Fadiman protocol in its frequency of administration and the addition of a supplemental component.

The Stamets protocol recommends taking a microdose of psilocybin mushrooms five days in a row, followed by two days off. This 5-on, 2-off schedule is designed to maximize the potential neuroplastic benefits of microdosing psilocybin. It’s worth noting that, like the Fadiman protocol, individual experiences may vary, and some users may prefer a different frequency or find that the Fadiman protocol works better for them.

An essential aspect of the Stamets protocol is the inclusion of two supplements: Lion’s Mane mushroom extract and niacin (vitamin B3). Both of these supplements have been shown to support brain health and cognitive function. The combination of psilocybin, Lion’s Mane, and niacin is believed to work synergistically to enhance the overall benefits of the microdosing experience.

Insights on Microdosing for Women

Dr. Pamela Kryskow, a physician and researcher who has studied microdosing and collaborates with Paul Stamets, has observed promising results in her work. In a presentation at the MAPS Psychedelic Science 2017 conference, she shared anecdotal reports from women who have found relief from various symptoms through microdosing. 

I’ve seen women who’ve reported improvements in mood, mental clarity, and a reduction in pain with microdosing.

~ Dr. Pamela Kryskow


Microdosing psychedelics is a promising avenue for those seeking to improve their mental and emotional well-being. By adhering to sub-hallucinogenic doses and following a responsible frequency of administration, individuals can potentially harness the benefits of these substances without compromising their daily functioning.

Whether you choose to follow the Fadiman protocol or the Stamets protocol, it’s essential to consult with a healthcare professional before embarking on a microdosing journey. Research in this area is still emerging, and more studies are needed to fully understand the long-term effects and safety of microdosing psychedelics.

In the meantime, continue to prioritize self-care, stay informed, and approach microdosing with curiosity, intention, and respect for the powerful substances involved.

Masterclass Replay: Unlocking the Potential of Microdosing Psychedelics for Women’s Health

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